Brain Lesions of Mice Intracerebrally Inoculated with Tyzzer's Organisms

Early lesions in cats inoculated with feline leukemia virus.

Tumefactive Brain Lesions in Patients with Neuromyelitis Optica Spectrum Disorder

Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct diagnosis.  Clinical P...

Decreases in Ms - Inoculated Mice

At present multiple sclerosis (MS) 1 presents a very complex medical problem. There are three fundamental reasons for this: first, the diagnosis of MS is extremely difficult (1) ; secondly, the etiology of the disease is unknown (2) ; and finally, a problem that is the keystone to the analysis of the other problems is the lack of a system, other than man, in which the disease can be studied. In...

Effectiveness of Cytoxan against Intracerebrally

In a previous study it was found that the lymphoid leukemia (L1210) of mice grew success fully when inoculated intracerebrally (I.C.). The leukemic cells grew in the brain, infiltrated dii fusely in the arachnoid, and became systemic in 2—8days following intracerebral inoculation. Also, when the leukemia was inoculated I.C., death oc curred somewhat sooner than when the leukemic cells were in...

Immune reactivity of Visna virus-inoculated mice.

Visna virus inoculation of mice before immunization with unrelated antigens caused suppression of humoral and cell-mediated immune responses. The immunosuppressive effect was dependent on the virus dose and time of administration. The number of "background" antibody-producing spleen cells increased slightly after inoculation of Visna virus. Heat treatment of Visna virus abolished its immunosupp...